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A beta zero-thalassemic beta-globin RNA that is labile in bone marrow cells is relatively stable in HeLa cells.

We have shown previously that a beta-globin RNA-deficient beta zero-thalassemia is caused by a single base-pair deletion in codon 44 of the human beta-globin gene1. The lack of beta-globin RNA in erythroid cells of these affected individuals is due to extreme beta-globin RNA instability (t 1/2 = 30...

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Bibliografske podrobnosti
Main Authors: Maquat, L E, Kinniburgh, A J
Format: Artigo
Jezik:Inglês
Izdano: 1985
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC341199/
https://ncbi.nlm.nih.gov/pubmed/2582366
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