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Zinc ions are differentially required for the transcription of ribosomal 5S RNA and tRNA in a HeLa-cell extract.

Chelation of divalent cations by 5 mM EDTA and subsequent removal by dialysis from a cytoplasmic HeLa cell extract leads to a complete loss of 5S rRNA transcription without affecting tRNA synthesis. Transcription complexes for 5S RNA can no longer be assembled in such a zinc-depleted extract and thi...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Wingender, E, Dilloo, D, Seifart, K H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1984
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6440120/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.23.8971
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