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Structural basis for intersubunit signaling in a protein disaggregating machine
ClpB is a ring-forming, ATP-dependent protein disaggregase that cooperates with the cognate Hsp70 system to recover functional protein from aggregates. How ClpB harnesses the energy of ATP binding and hydrolysis to facilitate the mechanical unfolding of previously aggregated, stress-damaged proteins...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411974/ https://ncbi.nlm.nih.gov/pubmed/22802670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207040109 |
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