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Large mutational target size for rapid emergence of bacterial persistence
Phenotypic heterogeneity displayed by a clonal bacterial population permits a small fraction of cells to survive prolonged exposure to antibiotics. Although first described over 60 y ago, the molecular mechanisms underlying this behavior, termed persistence, remain largely unknown. To systematically...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411964/ https://ncbi.nlm.nih.gov/pubmed/22802628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205124109 |
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