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Pre-mRNA splicing in disease and therapeutics
In metazoans, alternative splicing of genes is essential for regulating gene expression and contributing to functional complexity. Computational predictions, comparative genomics, and transcriptome profiling of normal and diseased tissues indicate an unexpectedly high fraction of diseases are caused...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411911/ https://ncbi.nlm.nih.gov/pubmed/22819011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.06.006 |
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