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IL-10 regulates Il12b expression via histone deacetylation: Implications for intestinal macrophage homeostasis

To prevent excessive inflammatory responses to commensal microbes, intestinal macrophages unlike their systemic counterparts do not produce inflammatory cytokines in response to enteric bacteria. Consequently, loss of macrophage tolerance to the enteric microbiota plays a central role in the pathoge...

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Detalhes bibliográficos
Main Authors: Kobayashi, Taku, Matsuoka, Katsuyoshi, Sheikh, Shehzad Z., Russo, Steven M., Mishima, Yoshiyuki, Collins, Colm, deZoeten, Edwin F., Karp, Christopher L., Ting, Jenny P. Y., Sartor, R. Balfour, Plevy, Scott E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411910/
https://ncbi.nlm.nih.gov/pubmed/22786766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200042
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