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Storage-Induced Changes in Erythrocyte Membrane Proteins Promote Recognition by Autoantibodies

Physiological erythrocyte removal is associated with a selective increase in expression of neoantigens on erythrocytes and their vesicles, and subsequent autologous antibody binding and phagocytosis. Chronic erythrocyte transfusion often leads to immunization and the formation of alloantibodies and...

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Detalhes bibliográficos
Main Authors: Dinkla, Sip, Novotný, Věra M. J., Joosten, Irma, Bosman, Giel J. C. G. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411782/
https://ncbi.nlm.nih.gov/pubmed/22879923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042250
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