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Membrane-Sensitive Conformational States of Helix 8 in the Metabotropic Glu2 Receptor, a Class C GPCR

The recent elucidation of the X-ray structure of several class A GPCRs clearly indicates that the amphipathic helix 8 (H8) is a conserved structural domain in most crystallized GPCRs. Very little is known about the presence and the possible role of an analogous H8 domain in the distantly related cla...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bruno, Agostino, Costantino, Gabriele, de Fabritiis, Gianni, Pastor, Manuel, Selent, Jana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411606/
https://ncbi.nlm.nih.gov/pubmed/22870276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042023
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