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Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation

The use of the lipid lowering agent niacin is hampered by a frequent flush response which is largely mediated by prostaglandin (PG) D(2). Therefore, concomitant administration of the D-type prostanoid (DP) receptor antagonist laropiprant has been proposed to be a useful approach in preventing niacin...

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Hlavní autoři: Philipose, Sonia, Konya, Viktoria, Lazarevic, Mirjana, Pasterk, Lisa M., Marsche, Gunther, Frank, Sasa, Peskar, Bernhard A., Heinemann, Akos, Schuligoi, Rufina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411562/
https://ncbi.nlm.nih.gov/pubmed/22870195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040222
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