Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation

The use of the lipid lowering agent niacin is hampered by a frequent flush response which is largely mediated by prostaglandin (PG) D(2). Therefore, concomitant administration of the D-type prostanoid (DP) receptor antagonist laropiprant has been proposed to be a useful approach in preventing niacin...

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Main Authors:	Philipose, Sonia, Konya, Viktoria, Lazarevic, Mirjana, Pasterk, Lisa M., Marsche, Gunther, Frank, Sasa, Peskar, Bernhard A., Heinemann, Akos, Schuligoi, Rufina
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2012
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3411562/ https://ncbi.nlm.nih.gov/pubmed/22870195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040222
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Laropiprant Attenuates EP3 and TP Prostanoid Receptor-Mediated Thrombus Formation

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