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ZIC1 modulates cell-cycle distributions and cell migration through regulation of sonic hedgehog, PI(3)K and MAPK signaling pathways in gastric cancer

BACKGROUND: ZIC1, a vital transcription factor with zinc finger domains, has been implicated in the process of neural development. We previously showed that ZIC1 may function as a tumour suppressor in gastrointestinal cancers. However, the molecular mechanism underlying ZIC1 participation in tumour...

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Autori principali: Zhong, Jing, Chen, Shujie, Xue, Meng, Du, Qin, Cai, Jianting, Jin, Hongchuan, Si, Jianmin, Wang, Liangjing
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411411/
https://ncbi.nlm.nih.gov/pubmed/22799764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-290
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