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Is S-nitrosylation of Cochlear Proteins a Critical Factor in Cisplatin-Induced Ototoxicity?

S-nitrosylation is a redox-sensitive protein modification, which is a highly specific, but reversible mechanism that regulates several signal transduction cascades. Oxidative stress plays a causal role in the ototoxic effects of an anti-neoplastic drug, cisplatin. Despite emerging evidence implicati...

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Sonraí Bibleagrafaíochta
Main Authors: Jamesdaniel, Samson, Manohar, Senthilvelan, Hinduja, Sneha
Formáid: Artigo
Teanga:Inglês
Foilsithe: Mary Ann Liebert, Inc. 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411336/
https://ncbi.nlm.nih.gov/pubmed/22524268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4656
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