Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver

[Image: see text] Activation of hepatic stellate cells (HSCs) and subsequent uncontrolled accumulation of altered extracellular matrix (ECM) underpin liver fibrosis, a wound healing response to chronic injury, which can lead to organ failure and death. We sought to catalogue the components of fibrot...

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Detalhes bibliográficos
Main Authors: Rashid, S. Tamir, Humphries, Jonathan D., Byron, Adam, Dhar, Ameet, Askari, Janet A., Selley, Julian N., Knight, David, Goldin, Robert D., Thursz, Mark, Humphries, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411196/
https://ncbi.nlm.nih.gov/pubmed/22694338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr3000927
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