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The Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocation

Insulin-stimulated glucose uptake by the glucose transporter GLUT4 plays a central role in whole-body glucose homeostasis, dysregulation of which leads to type 2 diabetes. However, the molecular components and mechanisms regulating insulin-stimulated glucose uptake remain largely unclear. Here, we d...

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Detalhes bibliográficos
Main Authors: Guo, Hui-Ling, Zhang, Cixiong, Liu, Qi, Li, Qinxi, Lian, Guili, Wu, Di, Li, Xuebin, Zhang, Wei, Shen, Yuemao, Ye, Zhiyun, Lin, Shu-Yong, Lin, Sheng-Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411167/
https://ncbi.nlm.nih.gov/pubmed/22473005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.52
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