Complexin arrests a pool of docked vesicles for fast Ca(2+)-dependent release

Regulated exocytosis requires that the assembly of the basic membrane fusion machinery is temporarily arrested. Synchronized membrane fusion is then caused by a specific trigger—a local rise of the Ca(2+) concentration. Using reconstituted giant unilamellar vesicles (GUVs), we have analysed the role...

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Hauptverfasser: Malsam, Jörg, Parisotto, Daniel, Bharat, Tanmay A M, Scheutzow, Andrea, Krause, Jean Michel, Briggs, John A G, Söllner, Thomas H
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411073/
https://ncbi.nlm.nih.gov/pubmed/22705946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.164
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