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Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

Respiratory complex II oxidizes succinate to fumarate as part of the Krebs cycle and reduces ubiquinone in the electron transport chain. Previous experimental evidence suggested that complex II is not a significant contributor to the production of reactive oxygen species (ROS) in isolated mitochondr...

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Bibliografske podrobnosti
Main Authors: Quinlan, Casey L., Orr, Adam L., Perevoshchikova, Irina V., Treberg, Jason R., Ackrell, Brian A., Brand, Martin D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411067/
https://ncbi.nlm.nih.gov/pubmed/22689576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374629
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