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Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

Respiratory complex II oxidizes succinate to fumarate as part of the Krebs cycle and reduces ubiquinone in the electron transport chain. Previous experimental evidence suggested that complex II is not a significant contributor to the production of reactive oxygen species (ROS) in isolated mitochondr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Quinlan, Casey L., Orr, Adam L., Perevoshchikova, Irina V., Treberg, Jason R., Ackrell, Brian A., Brand, Martin D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3411067/
https://ncbi.nlm.nih.gov/pubmed/22689576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374629
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