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Crystal Structure of the N-terminal Domain of the Yeast General Corepressor Tup1p and Its Functional Implications
The yeast Cyc8p-Tup1p protein complex is a general transcriptional corepressor of genes involved in many different physiological processes. Herein, we present the crystal structure of the Tup1p N-terminal domain (residues 1–92), essential for Tup1p self-assembly and interaction with Cyc8p. This doma...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410994/ https://ncbi.nlm.nih.gov/pubmed/22707714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369652 |
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