Crystal Structure of the N-terminal Domain of the Yeast General Corepressor Tup1p and Its Functional Implications

The yeast Cyc8p-Tup1p protein complex is a general transcriptional corepressor of genes involved in many different physiological processes. Herein, we present the crystal structure of the Tup1p N-terminal domain (residues 1–92), essential for Tup1p self-assembly and interaction with Cyc8p. This doma...

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Detalhes bibliográficos
Main Authors: Matsumura, Hiroyoshi, Kusaka, Nanoha, Nakamura, Taichi, Tanaka, Naoko, Sagegami, Keita, Uegaki, Koichi, Inoue, Tsuyoshi, Mukai, Yukio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410994/
https://ncbi.nlm.nih.gov/pubmed/22707714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369652
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