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IQGAP1 mediates the disruption of adherens junctions to promote Escherichia coli K1 invasion of brain endothelial cells

The transcellular entry of E. coli K1 through human brain microvascular endothelial cells (HBMEC) is responsible for tight junction disruption, leading to brain edema in neonatal meningitis. Previous studies demonstrated that outer membrane protein A (OmpA) of E. coli K1 interacts with its receptor,...

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Detalles Bibliográficos
Main Authors: Krishnan, Subramanian, Fernandez, G. Esteban, Sacks, David B., Prasadarao, Nemani V.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410974/
https://ncbi.nlm.nih.gov/pubmed/22519731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2012.01805.x
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