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Biotin-labeled synthetic oligodeoxyribonucleotides: chemical synthesis and uses as hybridization probes.
Oligodeoxynucleotides have been selectively labeled with biotin at their 5'-termini through an aminoalkylphosphoramide linker arm by an efficient chemical method. The reactions were performed in aqueous solution on unprotected oligonucleotides and were insensitive of the sequence and length of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1985
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC341094/ https://ncbi.nlm.nih.gov/pubmed/4000941 |
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