Antitumor Activity of Emodin against Pancreatic Cancer Depends on Its Dual Role: Promotion of Apoptosis and Suppression of Angiogenesis

BACKGROUND: Emodin has been showed to induce apoptosis of pancreatic cancer cells and inhibit tumor growth in our previous studies. This study was designed to investigate whether emodin could inhibit the angiogenesis of pancreatic cancer tissues and its mechanism. METHODOLOGY/PRINCIPAL FINDING: In a...

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Detalhes bibliográficos
Main Authors: Lin, Sheng-Zhang, Wei, Wei-Tian, Chen, Hui, Chen, Kang-Jie, Tong, Hong-Fei, Wang, Zhao-Hong, Ni, Zhong-Lin, Liu, Hai-Bin, Guo, Hong-Chun, Liu, Dian-Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410916/
https://ncbi.nlm.nih.gov/pubmed/22876305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042146
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