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The Importance of GLUT3 for De Novo Lipogenesis in Hypoxia-Induced Lipid Loading of Human Macrophages

Atherosclerotic lesions are characterized by lipid-loaded macrophages (foam cells) and hypoxic regions. Although it is well established that foam cells are produced by uptake of cholesterol from oxidized LDL, we previously showed that hypoxia also promotes foam cell formation even in the absence of...

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Sonraí Bibleagrafaíochta
Main Authors: Li, Lu, Liu, Bo, Håversen, Liliana, Lu, Emma, Magnusson, Lisa U., Ståhlman, Marcus, Borén, Jan, Bergström, Göran, Levin, Malin C., Hultén, Lillemor Mattsson
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410913/
https://ncbi.nlm.nih.gov/pubmed/22876317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042360
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