Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice

The aim was to clarify the role of vimentin, an intermediate filament protein abundantly expressed in activated macrophages and foam cells, in macrophages during atherogenesis. Global gene expression, lipid uptake, ROS, and inflammation were analyzed in bone-marrow derived macrophages from vimentin-...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Håversen, Liliana, Sundelin, Jeanna Perman, Mardinoglu, Adil, Rutberg, Mikael, Ståhlman, Marcus, Wilhelmsson, Ulrika, Hultén, Lillemor Mattsson, Pekny, Milos, Fogelstrand, Per, Bentzon, Jacob Fog, Levin, Malin, Borén, Jan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6242955/
https://ncbi.nlm.nih.gov/pubmed/30451917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34659-2
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak