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Comparison of the sequence specificity of bleomycin cleavage in two slightly different DNA sequences.

The sequence specificity of bleomycin damage was investigated utilising 340 bp alpha-DNA (a middle repetitive sequence in the human genome) as a target sequence. The following significant facts were found:- i) The dinucleotides GT and GC were cleaved on all occasions, GA most of the time, and AT, AC...

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Bibliografiske detaljer
Main Authors: Murray, V, Martin, R F
Format: Artigo
Sprog:Inglês
Udgivet: 1985
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC341089/
https://ncbi.nlm.nih.gov/pubmed/2582361
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