Rapid-Throughput Skeletal Phenotyping of 100 Knockout Mice Identifies 9 New Genes That Determine Bone Strength

Osteoporosis is a common polygenic disease and global healthcare priority but its genetic basis remains largely unknown. We report a high-throughput multi-parameter phenotype screen to identify functionally significant skeletal phenotypes in mice generated by the Wellcome Trust Sanger Institute Mous...

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Detalhes bibliográficos
Main Authors: Bassett, J. H. Duncan, Gogakos, Apostolos, White, Jacqueline K., Evans, Holly, Jacques, Richard M., van der Spek, Anne H., Ramirez-Solis, Ramiro, Ryder, Edward, Sunter, David, Boyde, Alan, Campbell, Michael J., Croucher, Peter I., Williams, Graham R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410859/
https://ncbi.nlm.nih.gov/pubmed/22876197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002858
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