PYY is a negative regulator of bone mass and strength

OBJECTIVE: Bone loss in anorexia nervosa and following bariatric surgery is associated with an elevated circulating concentration of the gastrointestinal, anorexigenic hormone, peptide YY (PYY). Selective deletion of the PYY receptor Y1R in osteoblasts or Y2R in the hypothalamus results in high bone...

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Udgivet i:Bone
Main Authors: Leitch, Victoria D., Brassill, Mary Jane, Rahman, Sofia, Butterfield, Natalie C., Ma, Pattara, Logan, John G., Boyde, Alan, Evans, Holly, Croucher, Peter I., Batterham, Rachel L., Williams, Graham R., Bassett, J.H. Duncan
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715792/
https://ncbi.nlm.nih.gov/pubmed/31306808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.07.011
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