Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation

BACKGROUND: Cathepsin C (Cat C) functions as a central coordinator for activation of many serine proteases in inflammatory cells. It has been recognized that Cat C is responsible for neutrophil recruitment and production of chemokines and cytokines in many inflammatory diseases. However, Cat C expre...

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Hauptverfasser: Fan, Kai, Wu, Xuefei, Fan, Bin, Li, Ning, Lin, Yongzhong, Yao, Yiwen, Ma, Jianmei
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410810/
https://ncbi.nlm.nih.gov/pubmed/22607609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-96
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