Delayed expression of cell cycle proteins contributes to astroglial scar formation and chronic inflammation after rat spinal cord contusion

BACKGROUND: Traumatic spinal cord injury (SCI) induces secondary tissue damage that is associated with astrogliosis and inflammation. We previously reported that acute upregulation of a cluster of cell-cycle-related genes contributes to post-mitotic cell death and secondary damage after SCI. However...

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Main Authors: Wu, Junfang, Pajoohesh-Ganji, Ahdeah, Stoica, Bogdan A, Dinizo, Michael, Guanciale, Kelsey, Faden, Alan I
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410790/
https://ncbi.nlm.nih.gov/pubmed/22784881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-169
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