GABA(B)-mediated rescue of altered excitatory–inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction

Reduced N-methyl-D-aspartate-receptor (NMDAR) signaling has been associated with schizophrenia, autism and intellectual disability. NMDAR-hypofunction is thought to contribute to social, cognitive and gamma (30–80 Hz) oscillatory abnormalities, phenotypes common to these disorders. However, circuit-...

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Главные авторы: Gandal, M J, Sisti, J, Klook, K, Ortinski, P I, Leitman, V, Liang, Y, Thieu, T, Anderson, R, Pierce, R C, Jonak, G, Gur, R E, Carlson, G, Siegel, S J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2012
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410621/
https://ncbi.nlm.nih.gov/pubmed/22806213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2012.69
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