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APECED: is this a model for failure of T cell and B cell tolerance?

In APECED, the key abnormality is in the T cell defect that may lead to tissue destruction chiefly in endocrine organs. Besides, APECED is characterized by high-titer antibodies against a wide variety of cytokines that could partly be responsible for the clinical symptoms during APECED, mainly chron...

詳細記述

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書誌詳細
主要な著者: Kluger, Nicolas, Ranki, Annamari, Krohn, Kai
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Research Foundation 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410439/
https://ncbi.nlm.nih.gov/pubmed/22876245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00232
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