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Analysis of a Jup hypomorphic allele reveals a critical threshold for postnatal viability
Mutations in the human Jup gene cause arrhythmogenic right ventricular cardiomyopathy (ARVC) a heart muscle disease that often leads to sudden cardiac death. Inactivation of the murine Jup gene (also known as plakoglobin) results in embryonic lethality due to cardiac rupture. In an effort to generat...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410040/ https://ncbi.nlm.nih.gov/pubmed/22522917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22034 |
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