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Cryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dynein

Cilia and flagella are highly conserved motile and sensory organelles in eukaryotes, and defects in ciliary assembly and motility cause many ciliopathies. The two-headed I1 inner arm dynein is a critical regulator of ciliary and flagellar beating. To understand I1 architecture and function better, w...

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Bibliografiske detaljer
Main Authors: Heuser, Thomas, Barber, Cynthia F., Lin, Jianfeng, Krell, Jeremy, Rebesco, Matthew, Porter, Mary E., Nicastro, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409752/
https://ncbi.nlm.nih.gov/pubmed/22733763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120690109
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