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Cryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dynein

Cilia and flagella are highly conserved motile and sensory organelles in eukaryotes, and defects in ciliary assembly and motility cause many ciliopathies. The two-headed I1 inner arm dynein is a critical regulator of ciliary and flagellar beating. To understand I1 architecture and function better, w...

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Detalhes bibliográficos
Main Authors: Heuser, Thomas, Barber, Cynthia F., Lin, Jianfeng, Krell, Jeremy, Rebesco, Matthew, Porter, Mary E., Nicastro, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409752/
https://ncbi.nlm.nih.gov/pubmed/22733763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120690109
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