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Structural analysis of a bacterial exo-α-d-N-acetylglucosaminidase in complex with an unusual disaccharide found in class III mucin

CpGH89 is a family 89 glycoside hydrolase with exo-α-d-N-acetylglucosaminidase activity that is produced by the human and animal pathogen Clostridium perfringens. This enzyme is active on the α-d-GlcpNAc-(1 → 4)-d-Galp motif that is displayed on the class III mucins within the gastric mucosa. Other...

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Bibliografiske detaljer
Main Authors: Ficko-Blean, Elizabeth, Boraston, Alisdair B
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409717/
https://ncbi.nlm.nih.gov/pubmed/22090394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwr165
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