IL6R Variation Asp(358)Ala Is a Potential Modifier of Lung Function in Asthma

BACKGROUND: The IL6R SNP rs4129267 has recently been identified as an asthma susceptibility locus in subjects of European ancestry but has not been characterized with respect to asthma severity. The SNP rs4129267 is in linkage disequilibrium (r(2)=1) with the IL6R coding SNP rs2228145 (Asp(358)Ala)....

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Main Authors: Hawkins, Gregory A, Robinson, Mac B, Hastie, Annette T, Li, Xingnan, Li, Huashi, Moore, Wendy C, Howard, Timothy D, Busse, William W., Erzurum, Serpil C., Wenzel, Sally E., Peters, Stephen P, Meyers, Deborah A, Bleecker, Eugene R
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409329/
https://ncbi.nlm.nih.gov/pubmed/22554704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.03.018
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