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Different Partners, Opposite Outcomes: A New Perspective of the Immunobiology of Indoleamine 2,3-Dioxygenase

Indoleamine 2,3-dioxygenase (IDO), a metabolic enzyme that catalyzes tryptophan conversion into kynurenines, is a crucial regulator of immunity. Altered IDO activity is often associated with pathology, including neoplasia and autoimmunity. IDO is highly expressed in dendritic cells (DCs) that exploi...

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書目詳細資料
Main Authors: Orabona, Ciriana, Pallotta, Maria Teresa, Grohmann, Ursula
格式: Artigo
語言:Inglês
出版: ScholarOne 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409287/
https://ncbi.nlm.nih.gov/pubmed/22481272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00029
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