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Adenosine deaminases that act on RNA induce reproducible changes in abundance and sequence of embryonic miRNAs
Adenosine deaminases that act on RNA bind double-stranded and structured RNAs and convert adenosines to inosines by hydrolytic deamination. Inosines are recognized as guanosines, and, hence, RNA editing alters the sequence information but also structure of RNAs. Editing by ADARs is widespread and es...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409260/ https://ncbi.nlm.nih.gov/pubmed/22310477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.133025.111 |
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