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Probing Cocaine-Antibody Interactions in Buffer and Human Serum

BACKGROUND: Despite progress in cocaine immunotherapy, the kinetic and thermodynamic properties of antibodies which bind to cocaine and its metabolites are not well understood. It is also not clear how the interactions between them differ in a complex matrix such as the serum present in the human bo...

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Detalhes bibliográficos
Main Authors: Ramakrishnan, Muthu, Alves De Melo, Fernando, Kinsey, Berma M., Ladbury, John E., Kosten, Thomas R., Orson, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409241/
https://ncbi.nlm.nih.gov/pubmed/22859949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040518
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