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Hapten Optimization for Cocaine Vaccine with Improved Cocaine Recognition

In the absence of any effective pharmacotherapy for cocaine addiction, immunotherapy is being actively pursued as a therapeutic intervention. While several different cocaine haptens have been explored to develop anti-cocaine antibodies, none of the hapten was successfully designed which had a proton...

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Main Authors: Ramakrishnan, Muthu, Kinsey, Berma M., Singh, Rana A., Kosten, Thomas R., Orson, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127111/
https://ncbi.nlm.nih.gov/pubmed/24803171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cbdd.12326
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