Neuronal Transcription Factors Induce Conversion of Human Glioma Cells to Neurons and Inhibit Tumorigenesis

Recent findings have demonstrated that the overexpression of lineage-specific transcription factors induces cell fate changes among diverse cell types. For example, neurons can be generated from mouse and human fibroblasts. It is well known that neurons are terminally differentiated cells that do no...

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Main Authors: Zhao, Junli, He, Hua, Zhou, Kechun, Ren, Yonggang, Shi, Zixiao, Wu, Zhiyuan, Wang, Yizheng, Lu, Yicheng, Jiao, Jianwei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409237/
https://ncbi.nlm.nih.gov/pubmed/22859994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041506
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