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Mapping Genetic Variants Associated with Beta-Adrenergic Responses in Inbred Mice

β-blockers and β-agonists are primarily used to treat cardiovascular diseases. Inter-individual variability in response to both drug classes is well recognized, yet the identity and relative contribution of the genetic players involved are poorly understood. This work is the first genome-wide associ...

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Detalhes bibliográficos
Main Authors: Hersch, Micha, Peter, Bastian, Kang, Hyun Min, Schüpfer, Fanny, Abriel, Hugues, Pedrazzini, Thierry, Eskin, Eleazar, Beckmann, Jacques S., Bergmann, Sven, Maurer, Fabienne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409184/
https://ncbi.nlm.nih.gov/pubmed/22859963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041032
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