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Mapping Genetic Variants Associated with Beta-Adrenergic Responses in Inbred Mice

β-blockers and β-agonists are primarily used to treat cardiovascular diseases. Inter-individual variability in response to both drug classes is well recognized, yet the identity and relative contribution of the genetic players involved are poorly understood. This work is the first genome-wide associ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hersch, Micha, Peter, Bastian, Kang, Hyun Min, Schüpfer, Fanny, Abriel, Hugues, Pedrazzini, Thierry, Eskin, Eleazar, Beckmann, Jacques S., Bergmann, Sven, Maurer, Fabienne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409184/
https://ncbi.nlm.nih.gov/pubmed/22859963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041032
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