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Folate status of gut microbiome affects Caenorhabditis elegans lifespan

In a paper in BMC Biology Virk et al. show that Caenorhabditis elegans lifespan is extended in response to a diet of folate-deficient Escherichia coli. The deficiencies in folate biosynthesis were due to an aroD mutation, or treatment of E. coli with sulfa drugs, which are mimics of the folate precu...

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Détails bibliographiques
Auteurs principaux: Nguyen, Theresa PT, Clarke, Catherine F
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409036/
https://ncbi.nlm.nih.gov/pubmed/22849295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-10-66
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