TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: Potential role of TRPM8 as a biomarker and target

Pancreatic adenocarcinoma is mostly fatal and generally resistant to conventional treatments, such that effective therapies with tolerable side effects are desperately needed. Ion channels including the transient receptor potential (TRP) channels have been implicated in human malignancies, but their...

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Bibliografiska uppgifter
Huvudupphovsmän: Yee, Nelson S., Brown, Robert D., Lee, Min Sun, Zhou, Weiqiang, Jensen, Chris, Gerke, Henning, Yee, Rosemary K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2012
Ämnen:
Bedside to Bench Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408969/
https://ncbi.nlm.nih.gov/pubmed/22555807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20079
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