TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: Potential role of TRPM8 as a biomarker and target

Pancreatic adenocarcinoma is mostly fatal and generally resistant to conventional treatments, such that effective therapies with tolerable side effects are desperately needed. Ion channels including the transient receptor potential (TRP) channels have been implicated in human malignancies, but their...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Yee, Nelson S., Brown, Robert D., Lee, Min Sun, Zhou, Weiqiang, Jensen, Chris, Gerke, Henning, Yee, Rosemary K.
التنسيق: Artigo
اللغة:Inglês
منشور في: Landes Bioscience 2012
الموضوعات:
Bedside to Bench Report
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408969/
https://ncbi.nlm.nih.gov/pubmed/22555807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20079
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