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Angiogenesis inhibitors increase tumor stem cells

The clinical efficacy of angiogenesis inhibitors targeting the vascular endothelial growth factor pathway has recently been met with numerous phase III failures that showed modest survival benefits. Understanding the resistance mechanisms of antiangiogenic therapy is essential to overcoming the limi...

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Autors principals: Chau, Cindy H., Figg, William D.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408967/
https://ncbi.nlm.nih.gov/pubmed/22441817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.19852
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