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Angiogenesis inhibitors increase tumor stem cells

The clinical efficacy of angiogenesis inhibitors targeting the vascular endothelial growth factor pathway has recently been met with numerous phase III failures that showed modest survival benefits. Understanding the resistance mechanisms of antiangiogenic therapy is essential to overcoming the limi...

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Bibliographic Details
Main Authors: Chau, Cindy H., Figg, William D.
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408967/
https://ncbi.nlm.nih.gov/pubmed/22441817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.19852
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