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Identification of Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) as a CD8(+) T-cell-defined human tumor antigen of human carcinomas

Hydroxysteroid (17β) dehydrogenase type 12 (HSD17B12) is a multifunctional isoenzyme functional in the conversion of estrone to estradiol (E2), and elongation of long-chain fatty acids, in particular the conversion of palmitic to archadonic (AA) acid, the precursor of sterols and the inflammatory me...

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Autors principals: Visus, Carmen, Ito, Diasuke, Dhir, Rajiv, Szczepanski, Miroslaw J., Chang, Yoo Jung, Latimer, Jean J., Grant, Stephen G., DeLeo, Albert B.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408891/
https://ncbi.nlm.nih.gov/pubmed/21409596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1001-y
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