Oligodendroglia metabolically support axons and contribute to neurodegeneration

Oligodendroglia support axon survival and function through mechanisms independent of myelination and their dysfunction leads to axon degeneration in several diseases. The cause of this degeneration has not been determined, but lack of energy metabolites such as glucose or lactate has been hypothesiz...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Youngjin, Morrison, Brett M., Li, Yun, Lengacher, Sylvain, Farah, Mohamed H., Hoffman, Paul N., Liu, Yiting, Tsingalia, Akivaga, Jin, Lin, Zhang, Ping-Wu, Pellerin, Luc, Magistretti, Pierre J., Rothstein, Jeffrey D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408792/
https://ncbi.nlm.nih.gov/pubmed/22801498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11314
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