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Oligodendroglia metabolically support axons and contribute to neurodegeneration

Oligodendroglia support axon survival and function through mechanisms independent of myelination and their dysfunction leads to axon degeneration in several diseases. The cause of this degeneration has not been determined, but lack of energy metabolites such as glucose or lactate has been hypothesiz...

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Autors principals: Lee, Youngjin, Morrison, Brett M., Li, Yun, Lengacher, Sylvain, Farah, Mohamed H., Hoffman, Paul N., Liu, Yiting, Tsingalia, Akivaga, Jin, Lin, Zhang, Ping-Wu, Pellerin, Luc, Magistretti, Pierre J., Rothstein, Jeffrey D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408792/
https://ncbi.nlm.nih.gov/pubmed/22801498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11314
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